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Kimihiro Shimizu Selected Research

Amino Acid Transport Systems (Amino Acid Transporter)

1/2019Expression of amino acid transporter (LAT1 and 4F2hc) in pulmonary pleomorphic carcinoma.
1/2015Clinical significance of coexpression of L-type amino acid transporter 1 (LAT1) and ASC amino acid transporter 2 (ASCT2) in lung adenocarcinoma.
1/2015Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer.
10/2013Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer.
12/2010Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer.
11/2010Comparison of L-type amino acid transporter 1 expression and L-[3-18F]-α-methyl tyrosine uptake in outcome of non-small cell lung cancer.
9/2010Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in surgically resectable stage III non-small cell lung cancer.
12/2009CD98 expression is associated with poor prognosis in resected non-small-cell lung cancer with lymph node metastases.
10/2009Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma.
6/2009L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas.
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Kimihiro Shimizu Research Topics

Disease

58Neoplasms (Cancer)
01/2022 - 07/2005
32Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 07/2005
29Lung Neoplasms (Lung Cancer)
11/2022 - 09/2002
13Adenocarcinoma
07/2020 - 06/2007
9Adenocarcinoma of Lung
09/2020 - 01/2010
9Carcinoma (Carcinomatosis)
10/2019 - 02/2003
8Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2020 - 02/2009
6Neoplasm Metastasis (Metastasis)
09/2019 - 02/2009
5Sarcoma (Soft Tissue Sarcoma)
06/2021 - 12/2008
4Hemorrhage
01/2022 - 02/2005
4Hypoxia (Hypoxemia)
01/2020 - 01/2018
4Colorectal Neoplasms (Colorectal Cancer)
01/2019 - 04/2013
3Wounds and Injuries (Trauma)
01/2022 - 01/2013
3Neuroendocrine Tumors (Neuroendocrine Tumor)
10/2021 - 01/2008
3Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2019 - 07/2010
3Pneumothorax
05/2016 - 01/2013
2Interstitial Lung Diseases (Interstitial Lung Disease)
07/2020 - 06/2007
2Fistula
05/2019 - 02/2005
2Thymoma (Thymic Carcinoma)
02/2019 - 06/2009
2Small Cell Carcinoma
01/2019 - 10/2010
2Large Cell Carcinoma
01/2019 - 10/2010
2Lymphatic Metastasis
10/2013 - 09/2010
2Chylothorax
01/2005 - 09/2002
1Mesothelioma
01/2022
1Pain (Aches)
01/2022
1Bronchopulmonary Sequestration (Pulmonary Sequestration)
03/2021
1Anaphylaxis (Anaphylactic Shock)
01/2021
1Cysts
01/2020
1Thymic epithelial tumor
01/2020

Drug/Important Bio-Agent (IBA)

17ErbB Receptors (EGF Receptor)IBA
01/2021 - 06/2007
16Amino Acid Transport Systems (Amino Acid Transporter)IBA
01/2019 - 11/2007
8Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2010 - 12/2008
7Tyrosine Kinase InhibitorsIBA
01/2021 - 06/2007
6Gefitinib (Iressa)FDA Link
09/2020 - 06/2007
6Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
01/2019 - 04/2009
5Glucose (Dextrose)FDA LinkGeneric
01/2020 - 11/2011
5Carcinoembryonic AntigenIBA
01/2019 - 07/2005
4Pharmaceutical PreparationsIBA
09/2020 - 10/2015
4Biomarkers (Surrogate Marker)IBA
09/2020 - 10/2013
4Proteins (Proteins, Gene)FDA Link
09/2020 - 07/2010
4NivolumabIBA
03/2020 - 01/2018
4Biological ProductsIBA
01/2020 - 03/2002
4Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
01/2020 - 01/2018
4GemcitabineFDA Link
10/2013 - 03/2008
4Deoxyglucose (2 Deoxy D glucose)IBA
11/2011 - 11/2007
4Heavy Chain Fusion Regulatory Protein 1IBA
09/2010 - 02/2009
3Anaplastic Lymphoma KinaseIBA
01/2021 - 09/2019
3Amino AcidsFDA Link
01/2020 - 08/2011
3FluorineIBA
01/2018 - 08/2011
3Indicators and Reagents (Reagents)IBA
03/2017 - 07/2005
3DNA (Deoxyribonucleic Acid)IBA
09/2014 - 06/2007
2PhosphoproteinsIBA
10/2021 - 10/2017
2RNA (Ribonucleic Acid)IBA
09/2020 - 01/2017
2StathminIBA
09/2020 - 10/2017
2CrizotinibIBA
07/2020 - 09/2019
2Immune Checkpoint InhibitorsIBA
03/2020 - 03/2018
2Tyrosine (L-Tyrosine)FDA Link
01/2020 - 11/2010
2Cisplatin (Platino)FDA LinkGeneric
11/2018 - 09/2009
2Codon (Codons)IBA
09/2014 - 01/2010
2Messenger RNA (mRNA)IBA
12/2010 - 07/2010
1TeaIBA
01/2022
1Hematoxylin (Haematoxylon)IBA
10/2021
1Chromogranin AIBA
10/2021
1Eosine Yellowish-(YS) (Eosin)IBA
10/2021
1SynaptophysinIBA
10/2021
1monoclonal antibody E9X9VIBA
06/2021
1Indocyanine Green (Cardio-Green)FDA LinkGeneric
03/2021
1Contrast MediaIBA
01/2021
1Qa-SNARE Proteins (Syntaxin)IBA
09/2020
1Carrier Proteins (Binding Protein)IBA
09/2020
1B7-H1 AntigenIBA
09/2020
1TubulinIBA
09/2020
1MicroRNAs (MicroRNA)IBA
09/2020
1alectinibIBA
07/2020
1Forkhead Transcription Factors (Forkhead Box Proteins)IBA
03/2020
1betaIG-H3 protein (keratoepithelin)IBA
03/2020
1Monoclonal AntibodiesIBA
02/2020
1CholesterolIBA
01/2020
1Glucose Transporter Type 1IBA
01/2020
1LigandsIBA
01/2020
1Immune Checkpoint ProteinsIBA
01/2020

Therapy/Procedure

11Segmental Mastectomy (Lumpectomy)
11/2022 - 10/2010
9Therapeutics
11/2018 - 11/2011
7Thoracotomy
01/2022 - 08/2005
6Drug Therapy (Chemotherapy)
10/2021 - 06/2007
6Lymph Node Excision (Lymph Node Dissection)
01/2014 - 09/2002
4Metastasectomy
01/2019 - 04/2013
2Minimally Invasive Surgical Procedures
06/2021 - 10/2014
2Radiotherapy
01/2021 - 09/2009
2Local Anesthesia
05/2019 - 01/2011
2Adjuvant Chemotherapy
11/2018 - 10/2016
2Surgical Instruments (Clip)
09/2016 - 01/2014
2Chest Tubes (Chest Tube)
01/2005 - 09/2002
1Surgical Staplers (Surgical Stapler)
01/2022
1Operative Time
01/2022
1Neoadjuvant Therapy
01/2022
1Analgesia
01/2022
1Intravenous Administration
03/2021
1Chemoradiotherapy
01/2021
1Precision Medicine
09/2020